Cerebral Palsy Telethon in Louisiana this Weekend

A local telethon will be held this weekend in Terrebonne, Louisiana for children with cerebral palsy in Louisiana. Funds raised will help provide children with cerebral palsy assistive devices, such as braces, wheel chairs and other medical equipment.

The Louisiana cerebral palsy telethon will be held at the Houma-Terrbonne Civic Center, in Houma, Louisiana, on Saturday between 4 p.m. and 10 p.m., and Sunday between 8 a.m. and 6 p.m. The Terrebonne Area Telethon for Cerebral Palsy of Louisiana will also be broadcast on Comcast channel 21 and Charter Communications channel 18.

Cerebral Palsy Deep Brain Stimulation May Improve Movement Problems

There has been promising new research into the use of electrical brain implants to restore some movement for people affected by cerebral palsy.

French researchers have placed electrical devices known as deep brain stimulators into 13 people who have cerebral palsy with dystonia-choreoathetosis. The stimulators, made by Medtronic, Inc., are already approved to treat Parkinson’s disease, severe obsessive-compulsive disorder, tremors and dystonia. Medtronic partially funded the study.

Dystonia-choreoathetosis is movement disorder that causes involuntary muscle contractions. It affects about 10% of all cerebral palsy patients and there are no known effective treatments.

A year into the research, improvement has been found in eight of the 13 subjects, while two showed no changes and three had their conditions worsen slightly, according to results published in the medical journal Lancet Neurology. Those who improved had an increase in motor control ranging from 21 to 55 percent. The treatment also reduced pain and had positive mental health effects on most of the subjects, though five subjects had to be treated with anti-anxiety medication.

The deep brain stimulators consist of electrodes placed in the globus pallidus internus area of the brain, which is the same area used to treat non-cerebral palsy dystonia patients. The leads are connected by wire to the main implant near the collar bone or abdomen. A generator inside the implant sends electrical pulses through the leads into the brain.

Researchers warned that the study was limited in scope, and called for further studies, but said that the results looked promising. It is unknown, however, how the implants would affect children with cerebral palsy or other, more complex forms of cerebral palsy.

REUTERS: Device Shows Promise to Treat Cerebral Palsy Type

Cerebral Palsy Speech Therapy Device

Some parents of children with cerebral palsy are finding that use of a speech therapy device originally approved to help stroke sufferers regain the ability to eat and swallow properly could also help increase their children’s ability to communicate.

VitalStim is an electrical device approved by the FDA for the treatment of dysphagia, or difficulty swallowing. Using external electrodes, VitalStim therapy stimulates muscles in the throat in order to help patients relearn to swallow properly.

A recent report by Ivanhoe describes how some parents and physical therapists have discovered that the device can also be used to improve mouth control for children with cerebral palsy.

Though only approved in 2002 for dysphagia, applying the device to the face muscles causes them to contract, strengthening them. Cerebral palsy patients using VitalStim are connected to the device for an hour-long session, three times a week, in conjunction with speech therapy. The electrodes of the VitalStim are applied to the face, and the device begins a continuous cycle of delivering current through the muscles, causing them to contract. Every minute, the device shuts down, and then cycles back up again. While the device is working, the therapist gets the child to do mouth and tongue exercises.

Cerebral Palsy Stem Cell Treatments Take Families Out of U.S.

Hopeful for the slightest chance to cure their children, some parents in the United States are starting to go abroad to seek out experimental stem cell treatment for cerebral palsy.

A recent article by McClatchy Newspapers highlighted the efforts of two California families who are hoping that stem cell treatments using cells from umbilical cord blood will help their young children with cerebral palsy. However, because stem cell research has been stifled in the United States since the turn of the century, they must travel to China to get the treatments.

Aleesha and Michael Klomp, of Hanford, were scheduled to take their son Gryphon, 2, to China last month to begin a six-week regimen of cord blood stem cell infusions. They had to raise $50,000 for medical fees and travel expenses, with no guarantee of success, or even improvement, in their son’s CP. In Fresno, Jennifer Schmidt is trying to raise enough to take her two-year old daughter, Brooke Schmidt-Jordan, to have similar therapy.

The controversy over stem cells has focused in the U.S. primarily on embryonic stem cells, which require the destruction of the fetus, but the backlash has spilled over into all forms of stem cell research. Some estimate that the U.S. is five to ten years behind in the emerging medical technology.

The new Obama administration likely heralds a change in U.S. policy which will put the country on course to cover lost scientific ground, but the families say they aren’t willing to wait for America to play “catch up” on a lost decade of stem cell medical research.

According to the article:

President Obama’s administration proposed looser restrictions on stem-cell research than those the Bush administration had enacted, yet it could be years before the United States catches up to other countries in therapies offered to the public.

The families don’t think their children have that much time.

“Why would I wait five years to help him?” asked Michael Klomp, a construction worker.

Although some experts in the U.S. have expressed doubts about the effectiveness of umbilical cord stem cell CP treatments, there have been some encouraging results.

While the overall standards of medical treatment in China do not meet those of the United States, Chinese medical facilities often have VIP wards with up-to-date laboratories and technology, according to the U.S. State Department. Most Chinese hospitals do not accept U.S. medical insurance, and often require cash up front to pay for procedures. Many Chinese facilities do not have the capabilities to deal with complications, such as extreme infections, and patients may have to be sent to another hospital or even sent back to the U.S. for proper treatment.

In recent years China has become a hot spot of experimental procedures, enticing foreigners with difficult-to-treat ailments and money to take their chances on procedures which have not met the high bar set by the U.S. Food and Drug Administration.

Read the full article: Families Are Taking Toddlers to China for Stem-Cell Treatments

Speech Software for Children with Cerebral Palsy

A new software program could help children with cerebral palsy and other disabilities communicate more quickly and naturally with family and teachers.

The How Was School Today? computer system is equipped with a battery of sensors and recording devices that keep track of a child’s activity throughout the day, and then helps the child turn the information into smooth, interactive speech. Developers and those who have tested the software say it is a first of its kind program that allows children with speech developmental problems to answer questions and provide feedback at an unparalleled speed.

The cerebral palsy speech software was developed jointly by Scottish scientists at the University of Aberdeen, the University of Dundee, and Capability Scotland. It takes information it gathers throughout the day and turns that information into a story using natural language and narration. Children with motor disabilities and limited or no speech can then use the software to talk about things they’ve experienced and even answer questions.

Teachers and other school personnel who interact with the child will have swipe cards that allow the computer to log who the child has interacted with during the day. Teachers can record data about what the child has been doing in class, and the system would even make use of menu barcodes to log what the student had for lunch.

All of the data is converted into short stories about what the child did during the day, which are then placed as icons on a computer screen that the child can key up with a variety of input devices, depending upon their abilities.

Currently, software aimed at allowing communications with disabled children is slow and laborious, and many children and their parents become frustrated with the slow pace and limited amount of information that is conveyed. The developers of How Was School Today? hope their new program will resolve just those issues.

The developers plan to expand the system to use in settings beyond school, and find ways to apply it to children with a variety of disabilities or developmental challenges.

Read:

Maryland Cerebral Palsy Verdict: $3,991,000

A Maryland jury awarded $3,991,000 to the family of a 9 year-old boy who developed cerebral palsy from a lack of oxygen to the brain before or during birth, which was found to have been caused by the medical negligence of an emergency room physician and obstetrician.

Read more about this Maryland cerebral palsy lawsuit

Cerebral Palsy Robotic Therapy at MIT

Engineers at MIT have made great breakthroughs in the use of robotic therapy to treat cerebral palsy and other brain injuries, helping children to better control of their arms and legs.

According to a press release earlier this month, MIT researchers say that the use of cerebral palsy robotic therapy has the potential to help children grow new pathways in the brain that could help them regain upper and lower body motor control lost due to the underlying brain damage that caused cerebral palsy.

The engineers have already successfully tested robotic device treatment on stroke patients, and they are now applying those results to expand the potential cerebral palsy treatment options.

The team’s robot-assisted therapy for cerebral palsy utilizes robot devices that gently guide limbs to move in the proper manner. Through repetition, and by getting the patient to want to move the limb, the brain can be convinced to regrow neural pathways destroyed by cerebral palsy, strokes and other brain damage. The new pathways can potentially allow the patient to regain some previously lost measure of limb control.

In the cerebral palsy robot therapy, children make use of a video game-like simulation by taking hold of a handle and guiding a robotic arm to grab an object. When they move in the wrong direction, or do not move at all, the machine gently guides them toward their goal.

MIT engineers say that about 400 repetitions per hour of therapy are needed to stimulate the proper brain activity, and that previous work with stroke patients show that the patient must make a conscious effort to want to improve motor control.

Pilot studies showed that 36 children saw a decrease in impairment and an increase in the smoothness of limb motion after the therapy.

Read More: Science Daily”

Magnesium Sulfate Reduces Risk of Cerebral Palsy

Recent research indicates that the administration of magnesium sulfate in women who are at risk of delivering premature, before 32 weeks gestation, reduces the risk of cerebral palsy by about 50%.

A 10-year study conducted at 18 centers in the United States was published in the August 28, 2008 issue of the New England Journal of Medicine, titled “The Beneficial Effects of Antenantal Magnesium Sulfate” (BEAM).

Magnesium sulfate is a chemical compound that is commonly used in obstetrics to prevent severe pre-eclampsia developing into eclampsia (life-threatening convulsions). It is also used to stall the convulsions of eclampsia. Pre-eclampsia is characterized by high blood pressure, protein in the urine and edema (swelling).
 
The BEAM trial studied the connection between cerebral palsy and magnesium sulfate by identifying 2,240 women who had a likely chance of delivery 2 months before their due date. While half of the women received magnesium sulfate intravenously, the other half received a placebo.

Children born to the women who were given magnesium sulfate were found to have a 50% lesser likelihood of delivering a child who developed cerebral palsy when compared to children born to the mothers who were given a placebo.

Researchers called the results a “substantial breakthrough in maternal fetal medicine.”

Cerebral Palsy Prevention in the Future May Involve Use of Medications Before C-Section

New research suggests that two compounds developed at Northwestern University could possibly be used in the future to treat infants at risk for compromised oxygen levels before a c-section to prevent cerebral palsy.

About 750,000 adults and children in the United States have some form of cerebral palsy, which is caused by brain damage suffered before, during or immediately after birth. It has been estimated that about 3 in every 1,000 infants born, or about 0.3%, and approximately 10,000 infants and babies born in the United States are diagnosed with cerebral palsy each year.

A study published online by the journal Annals of Neurology, suggests that it may be possible to develop a medication in the future to help reduce the risk of cerebral palsy in humans.

Researchers developed two compounds that selectively inhibited an enzyme responsible for nitric oxide production in the brain. Hypoxia or low oxygen flow from mother to fetus causes an increase in nitric oxide levels and leads to brain damage and cerebral palsy.

The study tested the two compounds on rabbits to study the possible preventative strategy for cerebral palsy, and found that administering the compounds a half-hour prior to the hypoxic event did protect the fetus from brain damage.

Use of the compounds in humans is still a long way off, and some have questioned whether it is practical and what other effects may be caused by giving it to many babies who ultimately do not need it.

Read more about the research into preventing cerebral palsy.